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In 1941, Dr. Hervey Cleckley revolutionized the understanding of psychopathy with his book The Mask of Sanity. Egocentrism and failure of empathy were the underlying drivers, but Cleckley chose his title to reflect the element that trumped those. If psychopaths were merely evil, they would not be a major threat. They wreak so much havoc that they should be obvious. Yet the majority have consistently eluded the law.

Cleckley worried about his title metaphor: psychopathy is not a two-dimensional cover that can be lifted off the face like a Halloween mask. It permeates the offender’s personality. Joy, grief, anxiety, or amusement—he can mimic any on cue. He knows the facial expressions, the voice modulation, and the body language. He’s not just conning you with a scheme, he’s conning you with his life. His entire personality is a fabrication, with the purpose of deceiving suckers like you.

Psychopaths take great personal pride in their deceptions and extract tremendous joy from them. Lies become the psychopath’s occupation, and when the truth will work, they lie for sport. “I like to con people,” one of Hare’s subjects told a researcher during an extended interview. “I’m conning you right now.”

Lying for amusement is so profound in psychopaths, it stands out as their signature characteristic. “Duping delight,” psychologist Paul Ekman dubbed it.

Cleckley spent five decades refining his research and publishing four further editions of The Mask of Sanity. It wasn’t until the 1970s that Robert Hare isolated twenty characteristics of the condition and created the Psychopathy Checklist, the basis for virtually all contemporary research. He also wrote the definitive book on the malady, Without Conscience.

The terminology got muckier. Sociopath was in introduced in the 1930s, initially as a broader term for antisocial behavior. Eventually, psychopath and sociopath became virtually synonymous. (Varying definitions for the latter have led to distinctions by some experts, but these are not uniformly accepted.) The primary reason for the competing terms is that each was adopted in different fields: criminologists and law enforcement personnel prefer psychopath; sociologists tend toward sociopath. Psychologists and psychiatrists are split, but most experts on the condition use psychopath, and the bulk of the research is based on Hare’s checklist. A third term, antisocial personality disorder, or APD, was introduced in the 1970s and remains the only diagnosis included in the latest edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM IV). However, it covers a much broader range of disorders than does psychopath and has been roundly rejected by leading researchers.

So where do psychopaths come from? Researchers are divided, with the majority suggesting a mixed role: nature leading, nurture following. Dr. Hare believes psychopaths are born with a powerful predisposition, which can be exacerbated by abuse or neglect. A correlation exists between psychopaths and unstable homes—and violent upbringings seem to turn fledgling psychopaths more vicious. But current data suggests those conditions do not cause the psychopathy; they only make a bad situation worse. It also appears that even the best parenting may be no match for a child born to be bad.

Symptoms appear so early, and so often in stable homes with normal siblings, that the condition seems to be inborn. Most parents report having been aware of disturbing signs before the child entered kindergarten. Dr. Hare described a five-year old girl repeatedly attempting to flush her kitten down the toilet. “I caught her just as she was about to try again,” the mother said. “She seemed quite unconcerned, maybe a bit angry—about being found out.” When the woman told her husband, the girl calmly denied the whole thing. Shame did not register; neither did fear. Psychopaths are not individuals losing touch with those emotions. They never developed them from the start.

Hare created a separate screening device for juveniles and identified hallmarks that appear during the school years: gratuitous lying, indifference to the pain of others, defiance of authority figures, unresponsiveness to reprimands or threatened punishment, petty theft, persistent aggression, cutting classes and breaking curfew, cruelty to animals, early experimentation with sex, and vandalism and setting fires. Eric bragged about nine of the ten hallmarks in his journal and on his Web site—for most of them, relentlessly. Only animal cruelty is missing.

At some point—as either a cause or an effect of psychopathy—the psychopath’s brain begins processing emotional responses differently. Early in his career, Dr. Hare recognized the anatomical difference. He submitted a paper analyzing the unusual brain waves of psychopaths to a scientific journal, which rejected it with a dismissive letter. “Those EEGs couldn’t have come from real people,” the editor wrote.

Exactly! Hare thought. Psychopaths are that different. Eric Harris baffled the public because we could not conceive of a human with his motives. Even Kate Battan would describe him as a teenager trying to act like an adult. But the angst we associate with teenagers was the least of Eric’s drives. His brain was never scanned, but it probably would have shown activity unrecognizable as human to most neurologists.

The fundamental nature of a psychopath is a failure to feel. A psychopath’s grasp of fear and suffering is particularly weak. Dr. Hare’s research team spent decades studying psychopaths in prison populations. They asked one psychopath to describe fear. “When I rob a bank, I notice that the teller shakes or becomes tongue-tied,” he said. “One barfed all over the money.” He found that puzzling. The researcher pushed him to describe his own fear. How would he feel with the gun pointed at him? The convict said he might hand over the money, get the hell out, or find a way to turn the tables. Those were responses, the researcher said. How would you feel? Feel? Why would he feel?

Researchers often compare psychopaths to robots or rogue computers, like HAL from 2001: A Space Odyssey— programmed only to satisfy their own objectives. That’s the closest approximation of their behavior, but the metaphor lacks nuance. Psychopaths feel something; Eric seemed to show sadness when his dog was sick, and he occasionally felt twinges of regret toward humans. But the signals come through dimly.

Cleckley described this as a poverty of emotional range. That’s a tricky concept, because psychopaths develop a handful of primitive emotions closely related to their own welfare. Three have been identified: anger, frustration, and rage. Psychopaths erupt with ferocious bouts of anger, which can get them labeled “emotional.” Look more closely, Cleckley advised: “The conviction dawns on those who observe him carefully that here we deal with a readiness of expression rather than a strength of feeling.” No love. No grief. Not even sorrow, really, or hope or despair about his own future. Psychopaths feel nothing deep, complex, or sustained. The psychopath was prone to “vexation, spite, quick and labile flashes of quasi-affection, peevish resentment, shallow moods of self-pity, puerile attitudes of vanity, absurd and showy poses of indignation.”

Cleckley could have been describing Eric Harris’s journal. “how dare you think that I and you are part of the same species when we are sooooooooo different,” Eric wrote. “you arent human. you are a robot…. and if you pissed me off in the past, you will die if I see you.”