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The blotting out of empathy as these people inflict damage on victims is almost always part of an emotional cycle that precipitates their cruel acts. Witness the emotional sequence that typically leads to a sex crime such as child molestation.17 The cycle begins with the molester feeling upset: angry, depressed, lonely. These sentiments might be triggered by, say, watching happy couples on TV, and then feeling depressed about being alone. The molester then seeks solace in a favored fantasy, typically about a warm friendship with a child; the fantasy becomes sexual and ends in masturbation. Afterward, the molester feels a temporary relief from the sadness, but the relief is short-lived; the depression and loneliness return even more strongly. The molester begins to think about acting out the fantasy, telling himself justifications like "I'm not doing any real harm if the child is not physically hurt" and "If a child really didn't want to have sex with me, she could stop it."

At this point the molester is seeing the child through the lens of the perverted fantasy, not with empathy for what a real child would feel in the situation. That emotional detachment characterizes everything that follows, from the ensuing plan to get a child alone, to the careful rehearsal of what will happen, and then the execution of the plan. All of it is pursued as though the child involved had no feelings of her own; instead the molester projects on her the cooperative attitude of the child in his fantasy. Her feelings—revulsion, fear, disgust—do not register. If they did, it would "ruin" things for the molester.

This utter lack of empathy for their victims is one of the main focuses of new treatments being devised for child molesters and other such offenders. In one of the most promising treatment programs, the offenders read heart-wrenching accounts of crimes like their own, told from the victim's perspective. They also watch videotapes of victims tearfully telling what it was like to be molested. The offenders then write about their own offense from the victim's point of view, imagining what the victim felt. They read this account to a therapy group, and try to answer questions about the assault from the victim's perspective. Finally, the offender goes through a simulated reenactment of the crime, this time playing the role of the victim.

William Pithers, the Vermont prison psychologist who developed this perspective-taking therapy, told me, "Empathy with the victim shifts perception so that the denial of pain, even in one's fantasies, is difficult" and so strengthens the men's motivation to fight their perverse sexual urges. Sex offenders who have been through the program in prison had only half the rate of subsequent offenses after release compared to those who had no such treatment. Without this initial empathy-inspired motivation, none of the rest of treatment will work.

While there may be some small hope for instilling a sense of empathy in offenders such as child molesters, there is much less for another criminal type, the psychopath (more recently called the sociopath as a psychiatric diagnosis). Psychopaths are notorious for being both charming and completely without remorse for even the most cruel and heartless acts. Psychopathy, the incapacity to feel empathy or compassion of any sort, or the least twinge of conscience, is one of the more perplexing of emotional defects. The heart of the psychopath's coldness seems to lie in an inability to make anything more than the shallowest of emotional connections. The cruelest of criminals, such as sadistic serial killers who delight in the suffering of their victims before they die, are the epitome of psychopathy.18

Psychopaths are also glib liars, willing to say anything to get what they want, and they manipulate their victims' emotions with the same cynicism. Consider the performance of Faro, a seventeen-year-old member of a Los Angeles gang who crippled a mother and her baby in a drive-by shooting, which he described with more pride than remorse. Driving in a car with Leon Bing, who was writing a book about the Los Angeles gangs the Crips and the Bloods, Faro wants to show off. Faro tells Bing he's "gonna look crazy" at the "two dudes" in the next car. As Bing recounts the exchange:

The driver, sensing that someone is looking at him, glances over at my car. His eyes connect with Faro's, widen for an instant. Then he breaks the contact, looks down, looks away. And there is no mistaking what I saw there in his eyes: It was fear.

Faro demonstrates the look he flashed at the next car for Bing:

He looks straight at me and everything about his face shifts and changes, as if by some trick of time-lapse photography. It becomes a nightmare face, and it is a scary thing to see. It tells you that if you return his stare, if you challenge this kid, you'd better be able to stand your ground. His look tells you that he doesn't care about anything, not your life and not his.19

Of course, in behavior as complex as crime, there are many plausible explanations that do not evoke a biological basis. One might be that a perverse kind of emotional skill—intimidating other people—has survival value in violent neighborhoods, as might turning to crime; in these cases too much empathy might be counterproductive. Indeed, an opportunistic lack of empathy may be a "virtue" in many roles in life, from "bad cop" police interrogator to corporate raider. Men who have been torturers for terrorist states, for example, describe how they learned to dissociate from the feelings of their victims in order to do their "job." There are many routes to manipulativeness.

One of the more ominous ways this absence of empathy may display itself was discovered by accident in a study of the most vicious of wife batterers. The research revealed a physiological anomaly among many of the most violent husbands, who regularly beat up their wives or threaten them with knives or guns: the husbands do so in a cold, calculating state rather than while being carried away by the heat of fury.20 As their anger mounts, the anomaly emerges: their heart rate drops, instead of climbing higher, as is ordinarily the case with mounting fury. This means they are growing physiologically calmer, even as they get more belligerent and abusive. Their violence appears to be a calculated act of terrorism, a method for controlling their wives by instilling fear.

These coolly brutal husbands are a breed apart from most other men who batter their wives. For one, they are far more likely to be violent outside the marriage as well, getting into bar fights and battling with coworkers and other family members. And while most men who become violent with their wives do so impulsively, out of rage after feeling rejected or jealous, or out of fear of abandonment, these calculating batterers will strike out at their wives seemingly for no reason at all—and once they start, nothing she does, including trying to leave, seems to restrain their violence.

Some researchers who study criminal psychopaths suspect their cold manipulativeness, such absence of empathy or caring, can sometimes stem from a neural defect.* A possible physiological basis of heartless psychopathy has been shown in two ways, both of which suggest the involvement of neural pathways to the limbic brain. In one, people's brain waves are measured as they try to decipher words that have been scrambled. The words are flashed very quickly, for just a tenth of a second or so. Most people react differently to emotional words such as kill than to neutral words such as chair: they can decide more quickly if the emotional word was scrambled, and their brains show a distinctive wave pattern in response to the emotional words, but not the neutral ones. But psychopaths have neither of these responses: their brains do not show the distinctive pattern in response to the emotional words, and they do not respond more quickly to them, suggesting a disruption in circuits between the verbal cortex, which recognizes the word, and the limbic brain, which attaches feeling to it.