Выбрать главу

Honjo T., Muramatsu M., and Fagarasan S., 2004. AID: How does it aid antibody diversity? Immunity, 20: 659–668.

Horcher M., Souabni A., and Busslinger M., 2001. Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis. Immunity 14: 779–790.

Huynh K.D. and Bardwell V.J., 1998. The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT. Oncogene 17: 2473–2484.

Huynh K.D., Fischle W, Verdin E., and Bardwell V.J., 2000. BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev. 14: 1810–1823.

Ikawa T., Kawamoto H., Wright L.Y.T., and Murre C., 2004. Longterm cultured E2A-deficient hematopoietic progenitor cells are pluripotent. Immunity, 20: 349–360.

Jankovic M., Casellas R., Yannoutsos N., Wardemann H., and Nussen-zweig M.C., 2004. RAGs and regulation of autoantibodies, ytow. Rev. Immunol. 22: 485–501.

Keller A.D. and Maniatis T., 1991. Identification and characterization of a novel repressor of [3-interferon gene expression. Genes Dev. 5: 868–879.

Kim K.C., Geng L., and Huang S., 2003. Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Res. 63: 7619–7623.

Kitamura D. and Rajewsky K., 1992. Targeted disruption of p chain m?embrane exon causes loss of heavy-chain allelic exclusion. Nature 556: 154–156.

Kosak S.T., Skok J.A., Medina K.L., Riblet R., Le Beau M.M., Fisher A.G., and Singh H., 2002. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296: 158–162.

Kovanen P.E. and Leonard W.J., 2004. Cytokines and immunodeficiency diseases: Critical roles of the ?c-dependent cytokines interleukins 2, 4,7,9,15, and 21, and their signaling pathways. Immunol. Rev., 202: 67–83.

Krangel M.S., 2003. Gene segment selection in V(D)J recombination: Accessibility and beyond. Nat. Immunol. 4: 624–630.

Kraus M., Alimzhanov M.B., Rajewsky N., and Rajewsky K., 2004. Survival of resting mature B lymphocytes depends on BCR signaling via the Iga/p heterodimer. Cell 117: 787–800.

Lee A.I., Fugmann S.D., Cowell L.G., Ptaszek L.M., Kelsoe G., and Schatz D.G., 2003. A functional analysis of the spacer of V(D)J recombination signal sequences. PLoS Biol. 1: 56–69.

Liang H.E., Hsu L.Y., Cado D., and Schlissel M.S., 2004. Variegated transcriptional activation of the immunoglobulin k locus in pre-B cells contnbutes to the allelic exclusion of light-chain expression. Cell 118: 19–29.

Linderson Y., Eberhard D., Malin S., Johansson A., Busslinger M., and Pettersson S., 2004. Corecruitment of the Grg4 repressor by PU.l is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep. 5: 291–296.

Maier H., Colbert J., Fitzsimmons D., Clark D.R., and Hagman J., 2003. Activation of the early B-cell-specific mb-1 (Ig-a) gene by Pax-5 is dependent on an unmethylated fits binding site. Mol. Cell. Biol. 23: 1946–1960.

Maier H., Ostraat R., Gao H., Fields S., Shinton S.A., Medina K.L., Ikawa T., Murre C., Singh H., Hardy R.R., and Hagman J., 2004. Early B cell factor cooperates with Runx 1 and mediates epigenetic changes associated with mb-1 transcription. Nat. Immunol. 5: 1069–1077.

Massari M.E., Grant P.A., Pray-Grant M.G., Berger S.L., Workman J.L., and Murre C., 1999. A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol. Cell. 4: 63–73.

McBlane F. and Boyes J., 2000. StimulationofV(D)J recombination by histone acetylation. Curr. Biol. 10: 483–486.

McMurry M.T. and Krangel M.S., 2000. A role for histone acetylation in the developmental regulation of V(D)J recombination. Science 287: 495–498.

Medina K.L., Pongubala J.M., Reddy K.L., Lancki D.W., DeKoter R., Kieslinger M., Grosschedl R., and Singh H., 2004. Assembling a gene regulatory network for specification of the B cell fate. Dev. Cell 7: 607–617.

Mikkola I., Heavey B., Horcher M., and Busslinger M., 2002. Reversion of B cell commitment upon loss of Pax5 expression. Science 297: 110–113.

Mito Y., Henikoff J.G., and Henikoff S., 2005. Genome-scale profiling of histone H3.3 replacement patterns. Nat Genet. 37: 1090–1097.

Miyamoto T., Iwasaki H., Reizis B., Ye M., Graf T., Weissman I.L., and Akashi K., 2002. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3: 137–147.

Morshead K.B., Ciccone D.N., Taverna S.D., Allis C.D., and Oettinger M.A., 2003. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc. Natl. Acad. Sci. USA 100: 11577-11582.

Mostoslavsky R., Singh N., Kirillov A., Pelanda R., Cedar H., Chess A., and Bergman Y., 1998. K chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev. 12: 1801–1811.

Mostoslavsky R., Singh N., Tenzen T., Goldmit M., Gabay C, Elizur S., Qi P., ReubinoffB.E., Chess A., Cedar H., and Bergman Y., 2001. Asynchronous replication and allelic exclusion in the immune system. Nature 414: 221–225.

Niu H., Ye B.H., and Dalla-Favera R., 1998. Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev. 12: 1953–1961.

Nutt S.L., Heavey B., Rolink A.G., and Busslinger M., 1999. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 Nature 401: 556–562.

Nutt S.L., Urbanek P., Rolink A., and Busslinger M., 1997. Essential functions of Pax5 (BSAP) in pro-B cell development: Difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. Genes Dev. 11: 476–491.

Orphanides G. and Reinberg D., 2000. RNA polymerase II elongation through chromatin. Nature 407: 471–475.

Osipovich O., Milley R., Meade A., Tachibana M., Shinkai Y., Krangel M.S., and Oltz E.M., 2004. Targeted inhibition ofV(D) J recombination by a histone methyltransferase. Nat. Immunol. 5: 309–316.

Peters A.H., O’Carroll D., Scherthan H., Mechtler K., Sauer S., Schufer C., Weipoltshammer K., Pagani M., Lachner M., Kohlmaier A., et al., 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107: 323–337.

Rajewsky K., 1996. Clonal selection and learning in the antibody system. Nature 381: 751–758.