2. Ehrenreich, B. and McIntosh, J. (1997). The new creationism. Nation, 9
June 1997.
3. Rose, S., Kamin, L. J. and Lewontin, R. C. (1984). Not in our genes.
Pantheon, London.
4. Brittan, S. (1998). Essays, moral, political and economic. Hume Papers on Public Policy, Vol. 6, no. 4. Edinburgh University Press, Edinburgh.
5. Reznek, L. (1997). Evil or ill? Justifying the insanity defence. Routledge, London.
6. Wilson, E. O. (1998). Consilience. Little, Brown, New York.
7. Darwin's views on free will are quoted in Wright, R. (1994). The moral animal. Pantheon, New York.
8. Silver, B. (1998). The ascent of science. Oxford University Press, Oxford.
9. Ayer, A. J. (1954). Philosophical essays. Macmillan, London.
10. Lyndon Eaves, quoted in Wright, L. (1997). Twins: genes, environment and mystery of identity. Weidenfeld and Nicolson, London.
I N D E X
ADA, 249 Asquith, Herbert, 294
Affymetrix, 267 asthma, 66-75
ageing, 196—205 Austad, Steven, 201—2
AIDS, 124-5, 265, 267—9 Avery, Oswald, 14-15
Alkaptonuria, 39, 52, 71 Avery, Roy, 14
Allison, Anthony, 141 Ayer, A. J., 313
Altman, Sidney, 18
Alzheimer's disease: baboon, 154-60
A P O - E 4 association with, 261-8 Bailey, Michael, 118
inheritance of, 54, 59, 273, 309 Bakewell, Robert, 272
American Lung Association, 68, 73 Baldwin, James Mark, 220-22, 230
Ames, Bruce, 233-4 Balfour, Arthur, 293
Amnion's horn, 227-8 Bateson, William, 39, 4 5 - 6 , 174
Amos, William, 111, 112 BCG, 69
Anderson, French, 248-9 Beadle, George, 47
Anderson, Gerry, 293 Beckwith-Wiedemann syndrome, 210
Angelman, Harry, 207-8 Bede, Venerable, 35
Angelman syndrome, 212-4 bell curve, The (R. J. Herrnstein, C.
apoptosis, 238-42 Murray), 86
Apple, 181 Belloc, Hilaire, 293
Applied Biosystems, 245 Bell Telephone Company, 155
Ardipithecus skeleton, 30 Berg, Paul, 244, 261
Aristode, 13, 16, 174, 184 Bickerton, Derek, 94-5
Ashkenazi Jews, 191-2 Binet, Alfred, 78, 88
Ashworth, Dawn, 132-3 Biogen, 245
338 G E N O M E
Blackburn, Elizabeth, 197 Cech, Thomas, 18
Blaese, Michael, 248—9 Cecil, Lord Robert, 295
Blanchard, Ray, 119 Celera, 246
Blanchflower, Danny, 266 cerebellar ataxia, 59
blood groups, 156—47 Cetus, 245
Blunt, Wilfred Scawen, 294 Chagas' disease, 157
BMP4, 179 Chaplin, Charlie, 136
Boas, Franz, 92 Chesterton, G. K., 293
Boer War (1899-1902), 288 chimpanzee, 24, 27-37, 127
Borna disease, 143 Chomsky, Noam, 9 2 - 3 , 103
Bouchard, Thomas, 82 chronic fatigue syndrome see ME
Bowman Gray Medical School, North Churchill, Winston, 294
Carolina, 170 Cline, Martin, 247
Brave new world (Aldous Huxley), 303 Clinique Medicale (Armand Trousseau), breast cancer see cancer 67
Brittan, Sam, 308 cloning, 212-3, 255-7
Broca's aphasia, 96, 101 Cold Spring Harbour Laboratory, 224, Brock report (1934), 296-7 238, 289
Brock, Sir Laurence, 296 Collins, John, 308
BSE (bovine spongiform encephalopathy), Colossus (computer), 15
59, 281—5 Columbia University, 46
Buck v Bell (1927), 290 'comma-free code', 50
Buck, Carrie, 290 Committee for the Prevention of Jewish Buck, Doris, 290 Genetic Disease, 191, 299
Buck, Emma, 290 Concepcion, Maria, 57
Buck, Vivian, 290 Consilience (Edward Wilson), 310
Buckland, Richard, 132-3 Cookson, William, 72-3
Burt, Cyril, 88 Coppens, Yves, 31
Butler, Samuel, 17 Correns, Carl, 44
Cortisol, 149-56
Caldicott, Dame Fiona, 265 Cosmides, Leda, 102-3
California Institute of Technology, 312 CREB, 224-6, 229, 302
California Supreme Court, 136 Creutzfeldt, Hans, 274
Calment, Jeanne, 203 Creutzfeldt-Jakob disease (CJD), 274—6, Calvin, John, 54, 56 278-80, 284-5
Cambrian explosion, 26, 180-1 Crick, Francis, 13, 14, 4 9 - 5 1 , 61, 138, cancer: 276, 280
breast, 190—1, 236 Culver, Kenneth, 250
D C C suppresses, 244 cyclic AMP, 223-4, 226
TP53 prevents, 233-42 cystic fibrosis, 142 see also Tay-Sachs Capecchi, Mario, 254-5 disease
Carnegie, Andrew, 289
Carter, Rita, 311 Daily Telegraph, 116
Cavalli-Sforza, Luigi Luca, 188-90 Dalton, John, 43
I N D E X 339
Darwin, Charles, 12, 43, 44—6, 93, 103—4, embryological development, 173-84
157—8, 287, 294, 310 embryonic stem cells, 254-7
Darwin, Erasmus, 12, 22 eugenics, 286—300
Darwin, Leonard, 294 Eugenics Education Society, 292-4
Davenport, Charles, 289 European Union, 151, 284
Davies, Michael, 160 Evolution: the four-billion year war (M.
Davis, Ronald, 226 Majerus, W. Amos, G. Hurst), 109
Dawkins, Richard, 26, 50, 104, 128
DAX, 110 Fabian Society, 292-3
de LaPlace, Pierre-Simon, 311 First World War (1914-18), 38, 79
Delbruck, Max, 13 Fisher, Sir Ronald, 42, 46, 291-2
de Miranda, Juan Carreno, 206 Fleming, Alexander, 2 5 8
Department of Health, 296 Flynn, James, 89-90
de Robertas, Eddie, 177 Focke, W. O., 44
Descartes, Rene, 47, 153 Forensic Science Service, 134
Descent of Man, The (Charles Darwin), 158 Forterre, Patrick, 20
de Silva, Ashanthi, 249 Frankenstein, 219, 251, 252
de Vries, Hugo, 44 Franklin, Rosalind, 13, 14
Diamond, Milton, 218 Freeman, Derek, 92
D N A : free will, 75, 301-13
ageing process and, 203 Freud, Sigmund, 92, 119, 218, 305—6
chimpanzee, 28 Friends of the Earth, 252
discovery of, 12-17 fruit fly, 129, 175—84
fingerprinting, 132-6 Furi, Sandra, 144-5
function of, 7 - 9
libraries, 246 Gajdusek, Carleton, 273-4, 277
'recombinant', 244, 248 Galton, Francis, 78, 85, 89, 90, 287-9, scrapie agent, 276 291, 298
'selfish', 124, 127-31, 212, 246 Gardner, Howard, 80
structure of, 49-53 Garrod, Archibald, 38-41, 46, 47, 52
Dolgopolsky, Aharon, 187 Garrod, Sir Alfred Baring, 38
Dolly, 208, 213, 255 Gehring, Walter, 177, 178
dopamine, 162-7 Genentech, 245
D o w n syndrome, 287-8, 298 genetically modified organisms, 251-7
du Chaiilu, Paul, 29 genetic engineering, 244-50
Dulbecco, Renato, 240 genetic imprinting, 210-18
Dunnet, George, 201 genetic screening, 261-9
Geron Corporation, 199, 20;
'East Side Story', 31 Gerstmann-Straussler-Scheinker disease, Eaves, Lyndon, 313 278
Ebstein, Richard, 163 Gibbs, Joe, 274
Eli Lilly, 168 Gladstone, Herbert, 293
Ellis, Havelock, 292 Goddard, H. H., 78, 79, 289
Epstein-Barr virus, 241 Gopnik, Myrna, 98-100
3 4 0 G E N O M E
Gould, Stephen Jay, 88, 306 Human Genome Project, 5, 145, 246
Great Ormond Street Hospital, 39 Hume, David, 309
Greenberg, Joseph, 187 Hume's fork, 301, 309
Greenpeace, 252 Huntington's chorea, 55-66, 75, 241, 264, Greider, Carol, 197 280
Grotewiel, Michael, 226 Huntington, George, 56
Gusella, Jim, 58 Huxley, Aldous, 303-4
Guthrie, Woody, 56, 57 Huxley, Julian, 292
Guy's Hospital, 60 Huxley, Thomas Henry, 29, 43
H-Y antigens, 119-21
Hadlow, Bill, 273-4
Haeckel, Ernst, 182, 288-9 ICE (interlocus contest evolution), 109, Haig, David, 3, 114, 209-11 116
Haldane, J. B. S., 146, 201, 292, 297 Identigene, 134
Hall, Peter, 235 IGF2R, 77, 87, 210