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Driving past remnants of the last Ice Age, she reflected on how insignificant humans are in the scheme of things. Suddenly she thought of Aldous Huxley's novelAfter Many a Summer Dies the Swan, about a wealthy madman who'd discovered a way to prolong life by eating the entrails of prehistoric fish. Maybe it was seeing the lake that made her flash on that.

She was now on Greenwood Lake Road, which passed around the west side, and there were numbers on several gated driveways as she passed along. She suspected the place would be somewhere along the middle of the lakeshore, and she was right.

After a few miles she came to a discreet sign announcing the Dorian Institute, and a large iron gate that protected a paved roadway leading into a forest of trees. That was it: just forest, no hint of a building, though she saw signs of some kind of industrial park farther down the road. When she drove up to the gate, she realized there was a video camera and a two-way intercom.

When she reached out of the window and pushed the talk button, she heard "Good morning." And then the gates parted in the middle and slid back.

They must be expecting us, she thought, and drove through.

The road was cobblestone, or rough paving brick. It wound among the trees for approximately half a mile and then widened.

There, framed by the lake in the background, was a magnificent three-story building with eight Doric columns across the front in perfect Greek Revival style. There were windows at ground level, but they were heavily curtained.

Built of red brick, the building probably dated from the late nineteenth century, and it looked every bit like an Ivy League dormitory.

"Miss Hampton, I don't like the feeling I'm getting about this place," Maria said quietly. "It is very cold and formal from the outside, but inside I sense a place where there is bad magic. In the Dominican Republic, we call it Santeria. I can always tell these things."

Ally knew and respected Maria's sixth sense. But then Maria sometimes still acted like a freshly minted citizen just off a green card, and she had an innate suspicion of authority- evoking buildings. Her aversion to the Dorian Institute might be nothing more than that.

On the other hand, Ally was having a bit of the same feeling. There was something formidable and foreboding about the place that seemed out of keeping with its supposedly benign purpose. She felt a moment of tightness in her chest.

There was a parking area off to the left, and she drove into the nearest slot and turned off her engine. This was the moment she'd been both anticipating and dreading. The clock on the dash read eleven-fifteen; she was fifteen minutes ahead of the appointed hour.

"Okay, Mom, how do you feel?"

Nina turned and stared at her, uncertainty in her eyes. "Where are we, Ally? I don't recognize anything."

"This is the institute I told you about last night. Can you remember anything we talked about then?"

"This is the place you were … Didn't you say there's a doctor here who can do something for my… memory?"

"We're both here now to just talk to him." She turned to the backseat. "Maria, can you get Mom's purse?"

She nodded, then reached hesitantly for the door. She was clearly reluctant to get out.

Ally walked around and opened the door for her mother.

"Okay, Mom, time to stretch your legs."

Ally held her hand and together they headed across the oval brick driveway. Birds were chirping around them and she could smell the scent of the lake, borne up the hill by a fresh wind. Then, through the trees, she saw two women walking up the trail that led down to the lake. They were, she assumed some of the patients.

They both looked to be in their early sixties, but also athletic and nimble. One was wearing Nikes and a pale green pantsuit. The other had on a blue dress and a white cap and Ally realized she must be a nurse. She'd been taking the other woman out for a stroll.

They were engrossed in conversation, but as they approached, the woman Ally had decided was on staff looked up and smiled a greeting.

"Can I help you?"

She introduced herself and Nina and Maria. The woman smiled again but didn't introduce herself in turn.

"We're here to see Dr. Van de Vliet," Ally went on, "about the trials. But we're a couple of minutes early and I was wondering if we could look around a bit first? I'm trying to understand what the institute is really like."

"Well, dear," the woman said, "even those of us who work here aren't allowed everywhere. You know, into the research lab in the basement. Some places here have to be completely hygienic. Of course, for patients who are in the recovery phase, strolling around outside is definitely recommended, as long as they're able. But that's getting way ahead of ourselves. First we'll have to check you in. There's a lot of paperwork for the clinical trials." She seemed puzzled. "They're almost over, you know. But come along and I'll let him know you're here. He's always down in the lab at this time of the morning. It's well after his rounds. They're so busy now."

Then she turned to the other woman. "Sophie, do you think you can find your way back to your room? It's number two-eighteen, on the second floor, remember?"

Sophie appeared to be pondering the question for a long moment before she huffed "Don't be silly. I know exactly where it is."

As she strode on ahead, the nurse watched her carefully, as though unsure what she might do next. She pushed a buzzer at the door and then a man in a white uniform opened it and let her in. Only after Sophie had disappeared through the doorway did the nurse turn back.

"I'm Elise Baker. Please forgive Sophie if she seems a little … confused. Her procedure is still under way."

"Her 'procedure'? What-"

"She was diagnosed with Parkinson's before she came here. She's improved an enormous amount, but we're not allowed to say so."

"Why is that?"

"We're in clinical trials. No one is allowed to discuss our results. Everyone here had to sign a secrecy agreement."

Now Maria was helping Nina up the steps. The porch, with its soaring white Doric columns, was definitely magisterial. The front door, however, was not wooden or decorative. It was solid steel, albeit painted white to blend in.

Elise walked to the door, which had a video camera mounted above it, and a split second later, it buzzed, signaling it was unlocked.

This is a lot of security, Ally thought,for a clinic doing research on cells.Are they worried about spies getting in, or patients getting out?

But the locked steel door was just the beginning of the security. Next they entered a small room just inside the door with an X-ray machine to see into purses and parcels.

"The first floor is reception and dining," Elise explained as she swept through the metal detector. "There are rooms-we call them suites-upstairs for patients, and the research lab and offices are in the. . lower area."

"What. . what is all this security for?" Ally asked.

"The work here is highly proprietary. No one is allowed to bring in any kind of camera or recording equipment."

The guard dressed in white looked like a retired policeman, with perhaps a few too many jelly doughnuts over his career. He had a beefy red face and a hefty spare tire. But he was certainly alert to his responsibilities, eyeing the three newcomers with scarcely disguised suspicion.

In fact, Ally sensed a palpable paranoia in the air.Well, she told herself, medical research is a high-stakes game.It's understandable they would be concerned about industrial espionage.

After the security check, they went through another steel door and entered the actual lobby. The first thing she noticed was a grand staircase leading up to the second floor, and then to the third. Off to the right was a modern elevator with a shiny steel door.