The second corroboration of the theory is by direct experiment, according to the canon of the Method of Difference. We can, by cooling the surface of any body, find in all cases some temperature (more or less inferior to that of the surrounding air, according to its hygrometric condition) at which dew will begin to be deposited. Here, too, therefore, the causation is directly proved. We can, it is true, accomplish this only on a small scale, but we have ample reason to conclude that the same operation, if conducted in nature’s great laboratory, would equally produce the effect.
And, finally, even on that great scale we are able to verify the result. The case is one of those rare cases, as we have shown them to be, in which nature works the experiment for us in the same manner in which we ourselves perform it; introducing into the previous state of things a single and perfectly definite new circumstance, and manifesting the effect so rapidly that there is not time for any other material change in the pre-existing circumstances. “It is observed that dew is never copiously deposited in situations much screened from the open sky, and not at all in a cloudy night; but if the clouds withdraw even for a few minutes, and leave a clear opening, a deposition of dew presently begins, and goes on increasing... Dew formed in clear intervals will often even evaporate again when the sky becomes thickly overcast.” The proof, therefore, is complete, that the presence or absence of an uninterrupted communication with the sky causes the deposition or non-deposition of dew. Now, since a clear sky is nothing but the absence of clouds, and it is a known property of clouds, as of all other bodies between which and any given object nothing intervenes but an elastic fluid, that they tend to raise or keep up the superficial temperature of the object by radiating heat to it, we see at once that the disappearance of clouds will cause the surface to cool; so that nature, in this case, produces a change in the antecedent by definite and known means, and the consequent follows accordingly: a natural experiment which satisfies the requisitions of the Method of Difference.[141]
The accumulated proof of which the Theory of Dew has been found susceptible, is a striking instance of the fullness of assurance which the inductive evidence of laws of causation may attain, in cases in which the invariable sequence is by no means obvious to a superficial view.
§ 4. The admirable physiological investigations of Dr. Brown-Séquard afford brilliant examples of the application of the Inductive Methods to a class of inquiries in which, for reasons which will presently be given, direct induction takes place under peculiar difficulties and disadvantages. As one of the most apt instances, I select his speculation (in the proceedings of the Royal Society for May 16, 1861) on the relations between muscular irritability, cadaveric rigidity, and putrefaction.
The law which Dr. Brown-Séquard’s investigation tends to establish, is the following: “The greater the degree of muscular irritability at the time of death, the later the cadaveric rigidity sets in, and the longer it lasts, and the later also putrefaction appears, and the slower it progresses.” One would say at first sight that the method here required must be that of Concomitant Variations. But this is a delusive appearance, arising from the circumstance that the conclusion to be tested is itself a fact of concomitant variations. For the establishment of that fact any of the Methods may be put in requisition, and it will be found that the fourth Method, though really employed, has only a subordinate place in this particular investigation.
The evidences by which Dr. Brown-Séquard establishes the law may be enumerated as follows:
1st. Paralyzed muscles have greater irritability than healthy muscles. Now, paralyzed muscles are later in assuming the cadaveric rigidity than healthy muscles, the rigidity lasts longer, and putrefaction sets in later, and proceeds more slowly.
Both these propositions had to be proved by experiment; and for the experiments which prove them, science is also indebted to Dr. Brown-Séquard. The former of the two—that paralyzed muscles have greater irritability than healthy muscles—he ascertained in various ways, but most decisively by “comparing the duration of irritability in a paralyzed muscle and in the corresponding healthy one of the opposite side, while they are both submitted to the same excitation.” He “often found, in experimenting in that way, that the paralyzed muscle remained irritable twice, three times, or even four times as long as the healthy one.” This is a case of induction by the Method of Difference. The two limbs, being those of the same animal, were presumed to differ in no circumstance material to the case except the paralysis, to the presence and absence of which, therefore, the difference in the muscular irritability was to be attributed. This assumption of complete resemblance in all material circumstances save one, evidently could not be safely made in any one pair of experiments, because the two legs of any given animal might be accidentally in very different pathological conditions; but if, besides taking pains to avoid any such difference, the experiment was repeated sufficiently often in different animals to exclude the supposition that any abnormal circumstance could be present in them all, the conditions of the Method of Difference were adequately secured.
In the same manner in which Dr. Brown-Séquard proved that paralyzed muscles have greater irritability, he also proved the correlative proposition respecting cadaveric rigidity and putrefaction. Having, by section of the roots of the sciatic nerve, and again of a lateral half of the spinal cord, produced paralysis in one hind leg of an animal while the other remained healthy, he found that not only did muscular irritability last much longer in the paralyzed limb, but rigidity set in later and ended later, and putrefaction began later and was less rapid than on the healthy side. This is a common case of the Method of Difference, requiring no comment. A further and very important corroboration was obtained by the same method. When the animal was killed, not shortly after the section of the nerve, but a month later, the effect was reversed; rigidity set in sooner, and lasted a shorter time, than in the healthy muscles. But after this lapse of time, the paralyzed muscles, having been kept by the paralysis in a state of rest, had lost a great part of their irritability, and instead of more, had become less irritable than those on the healthy side. This gives the A B C, a b c, and B C, b c, of the Method of Difference. One antecedent, increased irritability, being changed, and the other circumstances being the same, the consequence did not follow; and, moreover, when a new antecedent, contrary to the first, was supplied, it was followed by a contrary consequent. This instance is attended with the special advantage of proving that the retardation and prolongation of the rigidity do not depend directly on the paralysis, since that was the same in both the instances; but specifically on one effect of the paralysis, namely, the increased irritability; since they ceased when it ceased, and were reversed when it was reversed.
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I must, however, remark, that this example, which seems to militate against the assertion we made of the comparative inapplicability of the Method of Difference to cases of pure observation, is really one of those exceptions which, according to a proverbial expression, prove the general rule. For in this case, in which Nature, in her experiment, seems to have imitated the type of the experiments made by man, she has only succeeded in producing the likeness of man’s most imperfect experiments; namely, those in which, though he succeeds in producing the phenomenon, he does so by employing complex means, which he is unable perfectly to analyze, and can form, therefore, no sufficient judgment what portion of the effects may be due, not to the supposed cause, but to some unknown agency of the means by which that cause was produced. In the natural experiment which we are speaking of, the means used was the clearing off a canopy of clouds; and we certainly do not know sufficiently in what this process consists, or on what it depends, to be certain