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When Huxley left Europe for the United States in April 1937 he was at the height of his fame as a novelist and the Peace Pledge Union’s leading celebrity. Ironically, he was by now far more concerned with the virtues of non-attachment, anarchism, decentralisation and mystical salvation than with the failings of contemporary society, the role of pacifism in national politics or the art of fiction. If Huxley had been intent on exposing the meaninglessness of life in the 1920s, from the mid-1930s he was preoccupied with seeking the meaning of existence. Ends and Means (1937), in which Huxley tried ‘to relate the problems of domestic and international politics, of war and economics, of education, religion and ethics, to a theory of the ultimate nature of reality’, signalled his departure for the higher ground of mystical enlightenment where he would remain encamped for the rest of his life.

It was to lecture on the issues which dominate Ends and Means that Huxley and his friend and guru Gerald Heard had travelled to the United States. Huxley had every intention of returning to Europe, but his wife’s need to live in a hot, dry climate on health grounds and the lucrative prospect of writing for the movies contrived to keep the Huxleys in America until it was too unsafe to return. Huxley’s reaction to Hollywood and its cult of youth finds mordant expression in After Many a Summer (1939), the story of a Citizen Kane-like character’s life of grandiose illusion. The materialist excesses of Jo Stoyte are counterpointed by the ascetic convictions of Propter, a modern-day anchorite modelled on Heard. Huxley and Hollywood were not compatible, and his failure to write a popular play in the inter-war year was mirrored in his largely unsuccessful efforts to write for the movies. Walt Disney’s widely reported rejection of Huxley’s synopsis of Alice in Wonderland on the grounds that he ‘could only understand every third word’ was symptomatic of Huxley’s problem. His natural bent was for the leisurely and allusive development of an idea; above all else the movie moguls demanded pacey dialogue. His disenchantment with the world of the film studios is evident in the opening pages of Ape and Essence (1948), Huxley’s ghastly and graphic projection of Los Angeles as a ruinous, sprawling ossuary in the aftermath of the atomic Third World War. While the threat of global nuclear conflict has receded for the present, Huxley’s discussion of the rapid deforestation, pollution and other acts of ecological ‘imbecility’ which preceded the self-inflicted apocalypse he describes in the novel, is still chillingly topical.

Huxley spent most of the war years in a small house at Llano in the Mojave Desert in Southern California. In 1926 he had dismissed meditation as ‘the doze’s first cousin’, but it was to a life of quietistic contemplation that Huxley now devoted himself. This phrase of his career resulted in the excellent Grey Eminence (1941), a biography of Father Joseph, adviser to Cardinal Richelieu; Time Must Have a Stop (1944), a novel set in Florence in 1929 in which, to borrow Huxley’s words, ‘a piece of the Comédie Humaine… modulates into a vision of the Divina Commedia’; and The Perennial Philosophy (1945), a profoundly influential anthology of excerpts and commentaries illustrating what Huxley called ‘the highest common factor of all the higher religions’. He went on to say with typical humour and humility, ‘The greatest merit of the book is that about forty per cent of it is not by me, but by a lot of saints, many of whom were also men of genius.’ The Devils of Loudun, a compelling psychological study of sexual hysteria in seventeenth-century France, which was subsequently turned into a successful film, appeared in 1952. In the same way that Huxley’s astringent social satires caught the mood of the 1920s, so, in the years during and following the Second World War and the enormity of the Jewish Holocaust, his personal concern with spiritual and ethical matters and his consternation at the accelerating arms race reflected both the tone and unease of the zeitgeist.

Huxley also acquired new readers through his support of the marginal and unconventional, and his detractors, hitherto exercised by what they saw as his immorality or preachiness, began to pour scorn on his alleged faddism. In 1942 he published The Art of Seeing, a passionate defence of the Bates method of eye training which aroused a storm of protest from the optometrist lobby. Even more outrageous, for many, was his suggestion in The Doors of Perception (1954) and its sequel, Heaven and Hell (1956), that mescalin and lysergic acid were ‘drugs of unique distinction’ which should be exploited for the ‘supernaturally brilliant’ visionary experiences they offered to those with open minds and sound livers. The Doors of Perception is indeed a bewitching account of the inner shangri-la of the mescalin taker, where ‘there is neither work nor monotony’ but only ‘a perpetual present made up of one continually changing apocalypse’, where ‘the divine source of all existence’ is evident in a vase of flowers, and even the creases in a pair of trousers reveal ‘a labyrinth of endlessly significant complexity’. Not surprisingly, The Doors of Perception became a set text for the beat generation and the psychedelic Sixties, the Doors naming their band after the book which also earned Huxley a place on the sleeve of the Beatles’ Sergeant Pepper album.

Maria Huxley died in February 1955, shortly before Huxley published his penultimate novel, The Genius and the Goddess, in which John Rivers recounts the brief history of his disastrous involvement, when he was a ‘virgin prig of twenty-eight’, with the wife of his colleague Henry Maartens, a Nobel Prize-winning scientist. Not for the first time, Huxley’s theme is the havoc which ensues when a man with an idealistic misconception of life born of a cloistered and emotionally deprived upbringing experiences the full, sensual impact of human passion.