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Throughout our Galaxy and the multiverse, stellar evolution depends on whether and where intelligent life has evolved, and if so, on the outcomes of its wars and on how it treats its children. For example, we can predict roughly what proportions of stars of different colours (more precisely, of different spectral types) there should be in the Galaxy. To do that we shall have to make some assumptions about how much intelligent life there is out there, and what it has been doing (namely, that it has not been switching off too many stars). At the moment, our observations are consistent with there being no intelligent life outside our solar system. When our theories of the structure of our Galaxy are further refined, we shall be able to make more precise predictions, but again only on the basis of assumptions about the distribution and behaviour of intelligence in the Galaxy. If those assumptions are inaccurate we will predict the wrong distribution of spectral types just as surely as if we were to make a mistake about the composition of interstellar gases, or about the mass of the hydrogen atom. And, if we detect certain anomalies in the distribution of spectral types, this could be evidence of the presence of extraterrestrial intelligence. The cosmologists John Barrow and Frank Tipler have considered the astrophysical effects that life would have if it survived for long after the time at which the Sun would otherwise become a red giant. They have found that life would eventually make major, qualitative changes to the structure of the Galaxy, and later to the structure of the whole universe. (I shall return to these results in Chapter 14.) So once again, any theory of the structure of the universe in all but its earliest stages must take a position on what life will or will not be doing by then. There is no getting away from it: the future history of the universe depends on the future history of knowledge. Astrologers used to believe that cosmic events influence human affairs; science believed for centuries that neither influences the other. Now we see that human affairs influence cosmic events.

It is worth reflecting on where we went astray in underestimating the physical impact of life. It was by being too parochial. (That is ironic, because the ancient consensus happened to avoid our mistake by being even more parochial.) In the universe as we see it, life has affected nothing of any astrophysical significance. However, we see only the past, and it is only the past of what is spatially near us that we see in any detail. The further we look into the universe, the further back in time we see and the less detail we see. But even the whole past — the history of the universe from the Big Bang until now — is just a small part of physical reality. There is at least ten times as much history still to go, between now and the Big Crunch (if that happens), and probably a lot more, to say nothing of the other universes. We cannot observe any of this, but when we apply our best theories to the future of the stars, and of the galaxies and the universe, we find plenty of scope for life to affect and, in the long run, to dominate everything that happens, just as it now dominates the Earth’s biosphere.

The conventional argument for the insignificance of life gives too much weight to bulk quantities like size, mass and energy. In the parochial past and present these were and are good measures of astrophysical significance, but there is no reason within physics why that should continue to be so. Moreover, the biosphere itself already provides abundant counter-examples to the general applicability of such measures of significance. In the third century BC, for instance, the mass of the human race was about ten million tonnes. One might therefore conclude that it is unlikely that physical processes occurring in the third century BC and involving the motion of many times that mass could have been significantly affected by the presence or absence of human beings. But the Great Wall of China, whose mass is about three hundred million tonnes, was built at that time. Moving millions of tonnes of rock is the sort of thing that human beings do all the time. Nowadays it takes only a few dozen humans to excavate a million-tonne railway cutting or tunnel. (The point is made even more strongly if we make a fairer comparison, between the mass of rock shifted and the mass of that tiny part of the engineer’s, or emperor’s, brain that embodies the ideas, or memes, that cause the rock to be shifted.) The human race as a whole (or, if you like, its stock of memes) probably already has enough knowledge to destroy whole planets, if its survival depended on doing so. Even non-intelligent life has grossly transformed many times its own mass of the surface and atmosphere of the Earth. All the oxygen in our atmosphere, for instance about a thousand trillion tonnes — was created by plants and was therefore a side-effect of the replication of genes, i.e. molecules, which were descendants of a single molecule. Life achieves its effects not by being larger, more massive or more energetic than other physical processes, but by being more knowledgeable. In terms of its gross effect on the outcomes of physical processes, knowledge is at least as significant as any other physical quantity.

But is there, as the ancients assumed there must be in the case of life, a basic physical difference between knowledge-bearing and non-knowledge-bearing objects, a difference that depends neither on the objects’ environments nor on their effects on the remote future, but only on the objects’ immediate physical attributes? Remarkably, there is. To see what it is, we must take the multiverse view.

Consider the DNA of a living organism, such as a bear, and suppose that somewhere in one of its genes we find the sequence TCGTCGTTTC. That particular string of ten molecules, in the special niche consisting of the rest of the gene and its niche, is a replicator. It embodies a small but significant amount of knowledge. Now suppose, for the sake of argument, that we can find a junk-DNA (non-gene) segment in the bear’s DNA which also has the sequence TCGTCGTTTC. Nevertheless this sequence is not; worth calling a replicator, because it contributes almost nothing to its replication, and it embodies no knowledge. It is a random sequence. So here we have two physical objects, both segments of the same DNA chain, one of which embodies knowledge and the other is a random sequence. But they are physically identical. How can knowledge be a fundamental physical quantity, if one object has it while a physically identical object does not?

It can, because these two segments are not really identical. They only look identical when viewed from some universes, such as ours. Let us look at them again, as they appear in other universes. We cannot directly observe other universes, so we must use theory.

We know that DNA in living organisms is naturally subject to random variations — mutations — in the sequence of A, C, G and T molecules. According to the theory of evolution, the adaptations in genes, and therefore the genes’ very existence, depend on such mutations having occurred. Because of mutations, populations of any gene contain a degree of variation, and individuals carrying genes with higher degrees of adaptation tend to have more offspring than other individuals. Most variations in a gene make it unable to cause its replication, because the altered sequence no longer instructs the cell to manufacture anything useful. Others merely make replication less likely (that is, they narrow the gene’s niche). But some may happen to embody new instructions that make replication more likely. Thus natural selection occurs. With each generation of variation and replication the degree of adaptation of the surviving genes tends to increase. Now, a random mutation, caused for instance by a cosmic-ray strike, causes variation not only within the population of the organism in one universe, but between universes as well. A cosmic ‘ray’ is a high-energy sub-atomic particle and, like a photon emitted from a torch, it travels in different directions in different universes. So when a cosmic-ray particle strikes a DNA strand and causes a mutation, some of its counterparts in other universes are missing their copies of the DNA strand altogether, while others are striking it at different positions, and hence causing different mutations. Thus a single cosmic-ray strike on a single DNA molecule will in general cause a large range of different mutations to appear in different universes.